• The cast of Glee will feature in an episode
• Other guest stars include Facebook creator Mark Zuckerberg, Cheech and Chong, Wallace and Gromit, Jon Hamm, Daniel Radcliffe, Martha Stewart, Hugh Laurie, and Jonah Hill
• A teaser from Treehouse of Horror XXI was shown, in which board games come to life and wreak havoc on Springfield
• A teaser from this year’s Christmas special showed The Simpsons in puppet form
• 2011′s Christmas special will see The Simpsons 30 years in the future in which Bart, Lisa and Maggie bring their own kids over to Homer and Marge’s for Christmas.
• Al Jean reiterated “There’s no end in sight” for the show
• They won’t rule out the possibility of a spin-off; Matt Selmon says “Come on, Seth MacFarlane does one show three times”.

Thanks to the LA Times.

The voice cast were not present at the panel; however, showrunners Matt Groening and David X. Cohen were present, accompanied by writers and animators. Hypotoad was present to tell the audience to ignore the voice actors’ absence.

Both Matt and David adressed the issue; Matt said: “We love our ‘Futurama’ actors. We hope that Fox and the actors can come to an agreement as soon as possible.”; “Keep your fingers crossed. What’s going on right now is business” said David.

The good news, however, is that plenty of new information regarding the new season beginning next year was revealed.

The origins of Scruffy, the janitor will be revealed; Twitter will feature in an episode, controlled by Mom; Bender and Amy will get together, bringing up a robosexual marriage debate; The Professor and Fry find a time machine and end up in a very distant future; the reasons behind why the Professor hired Zoidberg will be revealed; Fry and Leela will be more romantic; Leela and Zapp will be together on an isolated planet; and a new Anthology of Interest episode is in the works.

A Futurama film for the big screen is also something Matt would love to do: “We’d love to do a Futurama theatrical feature, It’s really fun to see Futurama on the big screen”.

The panel for The Simpsons will take place on Saturday, July 25th, 2009 at 1:45pm. Here’s what Fox has to say about what we can expect from the panel:

Now entering its record-breaking 21st season on the air, The Simpsons is the longest-running series in the history of American television, and a household name around the world. Get a behind-the-scenes look at what’s coming up in the Simpsonverse, including never-before-seen highlights from the upcoming “Treehouse of Horror XX”, with a panel including Simpsons Creator Matt Groening, Showrunner Al Jean, Executive Producer Matt Selman and Supervising Director Mike Anderson.

Now that Futurama is back in production, it will also see representation at the convention:

1-1:45 PM: Life or Death?! BE A PART OF SCI-FI HISTORY! Join Executive Producers Matt Groening and David X. Cohen, and stars Billy West, Katey Sagal, John DiMaggio and Maurice LaMarche for high-stakes thrills as a top-ranking Fox executive decides live, on stage, whether Futurama will make yet another triumphant return, or whether it is gone forever! The very fate of Futurama hangs in the balance! Paramedics will be standing by in case the intense excitement causes any panelists to collapse. Raucous celebration or abject despair to follow the news.

The convention will begin on Friday, July 24th at the San Diego Convention Center in San Diego, California, and will run through to Sunday July 26th.